A ONCE-DAILY ORAL JAK inhibitor indicated for the treatment of adults and pediatric patients 12+ years of age with refractory, moderate to severe atopic dermatitis whose disease is not adequately controlled with other systemic drug products, including biologics, or when use of those therapies are inadvisable.1

DISRUPT

THE UNRELENTING
ITCH AND RASH OF
ATOPIC DERMATITIS
RINVOQ® is the first oral JAK inhibitor indicated for pediatrics 12 years and up.
RAPID
RELIEF1,2

EASI 75 measured at Week 16, and rates seen as early as Week 2

Reduced worst pruritus NRS ≥4 measured at Week 16, rates observed within 2 days after first dose

DURABLE
CONTROL1,3

Co-primary endpoints EASI 75 and vIGA 0/1 controlled at Week 16

Response rates observed up to 52 weeks

ROBUST
RESULTS1

90% skin improvement (EASI 90) measured at Week 16

WELL-STUDIED
SAFETY1,4-8

Clinical trial experience in >10,500 patients since 2012 across 5 approved indications

Commitment to exceptional access and patient support with

RINVOQ Complete logo

RINVOQ Complete offers patients the resources and support they need to start and stay on track with RINVOQ as prescribed.

for eligible patients who experience initial coverage delays or denials.

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ONE-TO-ONE
SUPPORT

Connects patients with Nurse Ambassadors* and Insurance Specialists

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ACCESS

Committed to exceptional national commercial coverage, providing access to the medicine patients are prescribed

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AFFORDABILITY

Eligible, commercially insured patients can save on their RINVOQ prescription and required lab tests

*Nurse Ambassadors are provided by AbbVie and do not provide medical advice or work under the direction of the prescribing health care professional (HCP). They are trained to direct patients to speak with their HCP about any treatment-related questions, including further referrals.

†Terms and Conditions apply. This benefit covers RINVOQ® (upadacitinib) alone or for RINVOQ plus one of the following medications: methotrexate, leflunomide, or hydroxychloroquine. Benefit also covers certain lab tests to monitor for specific parameters as recommended in the product label where the full cost is not covered by patients’ insurance through the Complete Rebate program (Maximum savings limit applies). Eligibility: Available to patients with commercial prescription insurance coverage for RINVOQ who meet eligibility criteria. Co‑pay assistance program is not available to patients receiving prescription reimbursement under any federal, state, or government‑funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law or by the patient’s health insurance provider. If at any time a patient begins receiving prescription drug coverage under any such federal, state, or government‑funded healthcare program, patient will no longer be able to use the RINVOQ Complete Savings Card and patient must call RINVOQ Complete at 1.800.2RINVOQ to stop participation. Patients residing in or receiving treatment in certain states may not be eligible. Patients may not seek reimbursement for value received from the RINVOQ Complete program from any third-party payers. Offer subject to change or discontinuance without notice. Restrictions, including monthly maximums, may apply. Patients who are members of insurance plans that claim to reduce or eliminate their patients' out of pocket co-pay, co-insurance, or deductible obligations for certain prescription drugs based upon the availability of, or patient's enrollment in, manufacturer sponsored co-pay assistance for such drugs (often termed "maximizer" programs) will have an annual maximum program benefit of $6,000.00 per calendar year. This assistance offer is not health insurance. By redeeming this card, you acknowledge that you are an eligible patient and that you understand and agree to comply with the terms and conditions of this offer. To learn about AbbVie’s privacy practices and your privacy choices, visit

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ONE PILL,
ONCE-DAILY

RINVOQ is an oral, once-daily therapy.1

For adults <65 years and pediatric patients 12+ years weighing at least 40 kg (88 lb), initiate treatment with RINVOQ 15 mg once-daily in pediatric patients (≥12 years, ≥40 kg) and adults <65 years of age. If an adequate response is not achieved, consider increasing the dosage to 30 mg once-daily. Discontinue RINVOQ if an adequate response is not achieved with the 30 mg dose. Use the lowest effective dose needed to maintain response. For patients ≥65 years, patients receiving strong CYP3A4 inhibitors, and patients with severe renal impairment, the recommended dose of RINVOQ is 15 mg once-daily. Coadministration of RINVOQ with strong CYP3A4 inducers is not recommended.1

RINVOQ® (upadacitinib) packaging. RINVOQ® (upadacitinib) packaging. RINVOQ® (upadacitinib) packaging.
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Want to learn about rapid skin clearance patients can see? In clinical studies
of RINVOQ, many patients achieved EASI 75 and vIGA 0/1 at Week 16.1

Itching to see more? See what patients experienced with RINVOQ in clinical trials.

Are your patients seeking treatment for the rash of atopic dermatitis?

Is itch a primary concern?

Safety is important to you. Want to know more about the safety profile of RINVOQ?

Want to know more about monitoring guidelines for RINVOQ?

RINVOQ Complete can help patients get the support they need to start
and stay on track with their prescribed treatment.

Familiar with Complete? RINVOQ Complete offers the same exceptional
AbbVie support you know and trust.

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